The vaccine Kolibin LCD Neo

Storage

One dose (2 ml) of the vaccine contains:

Active substance:

rotavirus bovine strain HM-91 (MSV-Bio-30), inactivated RP ≥ 1

Cattle coronavirus, strain C-197 (MSV-Bio-21), inactivated RP ≥ 1

Escherichia coli, enteropathogenic strains inactivated RP ≥ 1

MSLB strain 3014 (serotype O8: K35, K99)

MSLB strain 3015 (serotype O9: K35, K99)

MSLB strain 3016 (serotype O101: K35, K99)

Excipients:

preservative, thiomersal 0,085-0,115 mg / ml

inaktyvant: formaldehyde solution 35% ≤ 3,8 mg / ml

Adjuvant: montanid ISA 70 to 2 ml

Pharmaceutical form

Emulsion.

Immunobiological properties

The vaccine causes the formation of specific antibodies against viral and bacterial antigens are part of vaccines (bacteria Escherichia coli, rotavirus and coronavirus cattle).

Passive immunity in calves developed since the beginning of the use of colostrum derived from cows vaccinated and lasts for a period of feeding. Immunity in calves that consume colostrum naturally from vaccinated cows goes first 2-4 weeks of life.

Type of animal

Cattle.

Indications

For the active immunization of heifers and calf cows with calves to transfer passive immunity against diseases of the gastrointestinal tract caused by bacteria Escherichia coli, rotavirus and coronavirus cattle.

Contraindication

Do not vaccinate sick animals.

Caution when using

Before use, carefully shake the contents of the vial and warmed to a temperature (15-25) ° C. Vaccinate only clinically healthy animals. It is parent to vaccinate livestock animals. Calves should be given a sufficient amount of colostrum no later than six hours after birth.

Interaction with other drugs

Information about the harmlessness and efficacy of the vaccine with other veterinary drugs available. The decision to introduce a product with other veterinary medicines directly receives doctor of veterinary medicine.

Cautions during pregnancy, lactation

The vaccine is intended to apply to pregnant animals.

Dosage and Administration

The vaccine is used at a dose of 2 ml per animal by intramuscular injection into the thigh muscle. Calf cows and heifers are vaccinated twice with an interval of 21 days, namely for 7-5 weeks and 4-2 weeks before expected calving.

Further vaccination carried out once for 4-2 weeks before each subsequent calving.

Feeding colostrum:

To protect against infection in the first 2-3 weeks of life, calves should bring up a sufficient amount of colostrum derived from vaccinated cows. Colostrum (milk) is collected in the first 6-8 milking and keep frozen or chilled. Chilled colostrum (milk) retain a maximum of 14 days at 2 ° C to 8 ° C. Depending on the body weight of calves daily rate colostrum (milk) is 2.5-3.5 liters per animal for the first 2 weeks of life.

Side effects

In rare cases, after the vaccine may experience allergic reactions. If the manifestation of increased individual sensitivity using antihistamines.

Period output (karentsiyi)

Zero days.

Special precautions for staff and service personnel who use VIP

Avoid autovaktsynatsiyi. In case of accidental vaccine should immediately seek medical attention.

Special precautions for disposal of unused VIP, ways of disposal and recycling

Unused veterinary drug or empty bottles should be disposed of in accordance with local requirements.

Expiration date

2 years. The vaccine from an open bottle use within 10 hours.

Storage and transportation

Store in a dry, dark place at a temperature of 2 ° C to 8 ° C. Do not freeze!

Packaging

The vaccine comes in glass bottles capacity of 20 ml, 50 ml or 100 ml plastic bottles capacity of 10 ml, 100 ml, 250 ml. Bottles of vaccines covered with a rubber stopper suitable for piercing and sealed with aluminum cap, placed in cardboard boxes or plastic boxes with holes.

Size of packing:

Plastic boxes with 10 or 20 holes:

2 x 2 ml (4 doses of vaccine), 10 x 2 ml (20 doses of vaccine), 20 x 2 ml (40 doses of vaccine), 5 x 4 ml (10 doses of the vaccine), 10 x 4 ml (20 doses of vaccine) 5 x 10 ml (25 doses of vaccine), 10 x 10 ml (50 doses of vaccine).

Cardboard boxes 1 x 4 ml (2 doses of vaccine), 1 x 10 ml (5 doses of the vaccine), 1 x 20 ml (10 doses of the vaccine), 5 x 20 ml (50 doses of vaccine), 10 x 20 ml (100 doses vaccine), 1 x 50 ml (25 doses of vaccine), 12 x 50 ml (300 doses of vaccine), 24 x 50 ml (600 doses of vaccine), 1 x 100 ml (50 doses of vaccine), 12 x 100 ml (600 doses vaccines), 20 x 100 ml (1000 doses of vaccine), 1 x 250 ml (125 doses of vaccine), 12 x 250 ml (1500 doses of vaccine), 20 x 250 ml (2500 doses of vaccine).

Name and address of authorization holder and manufacturer

The company "Bioveta" Komenskeho 212 683 23 Ivanovitse on Hane, Czech Republic.

Additional Information

If the drug does not comply with the tab cards, or having complications, use this series to immediately stop and notify the State Scientific Control Institute of Biotechnology and strains (DNKIBSHM) and supplier (manufacturer). Along with DNKIBSHM messenger in direct, according to the "Guidelines on the procedure for filing claims against biological agents that are intended for use in veterinary medicine" from 03.06.98 number 2, three unopened vials of the drug in this series at 03151, m. Kyiv, st. Donetsk, 30 DNKIBSHM.