• Loksicum 2% solution for injection

Loksicum 2% solution for injection

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Product Code:
Vemedim corporation
Brand:
Vemedim corporation
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Storage:

1 ml of the drug contains the active substance: meloxicam - 20 mg. Excipients: ethanol, water for injections.

Pharmacological properties:

ATC vet classification code QM01A - anti-inflammatory and anti-rheumatic drugs, non-steroidal. QM01AC56 - Meloxicam. Meloxicam is a non-steroidal anti-inflammatory agent based on enolic acid, a class of oxycamines. It inhibits the synthesis of prostaglandins, which are mediators of inflammation, and thus causes anti-inflammatory, anti-exudative, analgesic and antipyretic effects. Reduces infiltration of leukocytes of tissues. To a small extent, it also suppresses collagen-induced platelet aggregation. Meloxicam also has antitoxic properties that are associated with inhibition of the production of thromboxydase B2, which occurs under the influence of endotoxins E. coli. The bioavailability of meloxicam after an intravenous injection reaches almost 100%. The highest level of absorption is achieved after 7.7 hours and 4 hours after application of the preparation for the body and lactating cows, respectively, and also 1 hour after application to pigs. Meloxicam is bound to plasma proteins more than 98%. The highest concentration of meloxicam after application is in the liver and kidneys, and the lowest in skeletal muscle and adipose tissue. All major metabolites of meloxicam are pharmacologically inactive. Metabolism in horses was not investigated. The half-life of meloxicam after subcutaneous administration is 26 hours and 17.5 hours in calves and lactating cows, respectively. Isolated from the body, mainly with milk and bile marrow, as well as with urine and faeces.

Application:

Cattle: treatment of animals for acute inflammation of the respiratory system (in the case of appropriate antibiotic therapy); as an auxiliary treatment for calves (older than 1 week), diarrhea patients; for acute mastosis in cows (as an additional therapy); to reduce postoperative pain after removing horns in the tedium.


Pigs: treatment of animals by the pathology of the musculoskeletal system (for the reduction of inflammation and pain), as well as auxiliary therapy for the treatment of postpartum sepsis and toxemia (mastitis-metritis-agalactia syndrome) for the administration of appropriate antibiotic therapy.


Horses: to reduce inflammation and pain in acute and chronic forms of inflammatory processes of the locomotor system and in colic (as an anti-inflammatory and analgesic).

Dosage:

Cattle: subcutaneously or intravenously in a dose of 2.5 ml of the preparation per 100 kg of body weight (0.5 mg of meloxicam per 1 kg of body weight) once. The recommended maximum volume of the drug for administration in one place is 10.0 ml. Pigs: intramuscularly in a dose of 2.0 ml of the preparation per 100 kg of body weight (0.4 mg of meloxicam per 1 kg of body weight) once. If necessary, repeat the injection after 24 hours. The recommended maximum dose for one place is 2.0 ml. Horses: intravenously in a dose of 3.0 ml of the preparation per 100 kg of body weight (0.6 mg of meloxicam per 1 kg of body weight) once.

Contraindication:

Do not use animals with a high sensitivity to the active substance or to any of the excipients. Do not use animals with impaired liver function, heart and kidneys, with possible ulcers or hematopoiesis in the digestive tract, with pathological changes in blood. Do not use calves under the age of 1 week. Do not apply horses up to 6 weeks old. Do not use the product with a chipmunk and during lactation. Do not use at the same time as glucocorticoids, other non-steroidal anti-inflammatory drugs and anticoagulants.

Karenia:

Slaughter of animals for meat is allowed after 15 days (cattle) and 5 days (pigs, horses) after the last application of the drug. Milk consumption allows 5 days after the last administration of the drug. Obtained, before the specified date, meat and milk are disposed of or fed by unproductive animals, depending on the conclusion of the veterinary medicine physician.

Release Type:

Vials of dark glass covered with rubber crumbs under an aluminum rim for 20, 50 and 100 ml

Storage:

dry dark, not accessible to children at a temperature from 2 ° C to 25 ° C. After the first selection from the vial, the drug should be used within 28 days, provided it is stored in a dark place at a temperature of 2 ° C to 8 ° C.

Expiration date:

2 years

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